Two Pfizer and BioNTech Covid 19 vaccine boosters updated to target the Omicron variant show a substantially higher immune response than the current
Two Pfizer and BioNTech Covid 19 vaccine boosters updated to target the Omicron variant show a substantially higher immune response than the current Covid 19 vaccine, the companies said, reported BBC. The companies tested a vaccine that targets Omicron BA.1 subvariant and bivalent booster, which targets two strains, that includes the current Pfizer/BioNTech Covid 19 vaccine and a vaccine candidate that targets Omicron. The study looked at two different dose levels, 30 micrograms and 60 micrograms, in more than 1,200 adults age 56 and older. The current primary and booster dosage for this age group is 30 micrograms.
The study showed that, across both dose levels, a fourth booster with the Omicron-modified vaccine candidates resulted in a substantially higher immune response against the variant. One month after the shot, the monovalent vaccine showed a 13.5- and 19.6-fold increase in Omicron-fighting antibodies, depending on the dose. The bivalent vaccine showed a 9.1 and 10.9-fold increase in antibodies. Preliminary results from studies in the lab also suggest the vaccines could neutralize the Omicron BA.4 and BA.5, the companies said. The BA.4 and BA.5 subvariants are increasingly circulating in the United States. Both vaccine candidates appeared to be safe and well-tolerated. “Based on these data, we believe we have two very strong Omicron-modified candidates that elicit a substantially higher immune response against Omicron than we’ve seen to date,” Pfizer Chairman and Chief Executive Officer Albert Bourla said in a news release.
Watch against contagion
In the last 24 hours 66 new cases of contagion and 0 deaths caused by Covid 19 were reported by State and Health Authorities. Contagion is being watched in Guanajuato and cases of contagion reported are below 70 in the last 24 hours, while there were 0 deaths reported. Authorities maintain the color of activities in the GREEN easing restrictions on activities, both leisure and work.
State Health Authorities insist that Guanajuato should maintain health protection.
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